بررسی اثرات بی حسی تزریق داخل نخاعی مپریدین و لیدوکائین 5% در بیمارانی که تحت عمل رزکسیون پروستات از راه مجرا قرار می گیرند

The aim of this study was a comparison between intrathecal meperidine    and lidocaine 5% for onset of sensory blockade, level of sensory block,    degree of motor blockade , duration of postoperative analgesia,    hemodynamic changes, degree of nausea and Vomiting, pruritus and    shivering for T.U.R Operation.          60 patients with ASA I-III were divided randomly into intrathecal    meperidine goup (n=30) and 5% lidocaine group (n=30). The first group    received 1 mg/kg (2ml) meperidine and the second group received     100 mg of 5% lidocaine (2ml).  Thirty minutes before subarachnoid puncture    all of the patients received 500ml ringer solution. Subarachnoid puncture    was performed with the patient in the sitting position using a 23 gauge    spinal needle at the lumbar level of L3-L4 and the patient immediately in the    supine position.           The onset time for sensory blockade was 3.99 minutes in the lidocaine    group and 5 minutes in the meperidine group. The segmental level of    analgesia was present in 28 patients in the lidicaine group .Duration of    post operative analgesia was 354 minutes in the lidicanie group and 662    minute in the meperidine group. Systolic arterial blood pressure and heart    rate did not change significantly , and there was no difference between    meperidine and lidocaine groups. Complication such as nausea and    vomiting were similar in the two groups, but pruritus was seen only in patients    receiving meperidine , and intraoperative sedation occurred in patients    receiving meperidine more than the other group. No patients who    received meperidine had postoperative shivering.           So according to this study, Intrathecal meperidine used alone has    advantages over lidocaine 5% for T.U.R. operation.